Investigative Ophthalmology & Visual Science – Saffron supplement mantains morphology and function after exposure to damaging light in mammalian retina

Rockville (USA), Marzo 2008 – In recent years, the impact of nutrition on the manifestation and progression of retinal diseases has become an important and controversial topic.
The antiapoptotic characteristics of the major components of saffron and its role in oxygen diffusibility made it of interest for conditions that affect retinal photoreceptors. In the paper are reported data showing that prefeeding with saffron provides striking protection against the death of photoreceptors induced by exposure to continuous bright light.
All experiments were performed in compliance with the Animal Care and Use Committee guidelines and in accordance with the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research.
Stigmas of saffron (L’Aquila Saffron; Antica Azienda Agricola Peltuinum, Prata D’Ansidonia, Italy) were dissolved in water to obtain a suspension, and 1 mg/kg was directly offered every day through a syringe.
Investigative Ophthalmology & Visual Science (IOVS),,  is an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purposes are to encourage and assist research, training, publication, and dissemination of knowledge in vision and ophthalmology.

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